SYNGAP1, a synaptic Ras GTPase activating protein deficiency is associated with severe intellectual disability in humans. Zebrafish...

A number of new drugs for neurodegenerative and inflammatory disease focus on target sites primarily within the brain. With human ED50 at...

Neuroactive Insecticide Bioactivity Testing

There is a need to understand fundamental mechanisms that leads to dysregulation trigger; which eventually leads up to neurodegeneration....

Gene editing primarily focus on threshold of edited protein as an Index of success rate. However in almost all cases, gene editing is met...

mRNA therapeutic applications are growing, however at the clinical stage, they are facing a similar failure rate as of small molecules !...

Key Hallmarks of the Assay: Cortical readings from zebrafish ALS models are generated with the similar sensitivity and readouts as in...

Current Clinical Challenges: In progressive Rheumatoid Arthritis (RA) candidates are designed to target inflammatory mediators -...

Fish swim against water current to spawn, feed and to stay within a particular habitat. This natural motion against water current is...

Real word Data points to directions away from monotherapies. From lessons learned, the risk of severe side effects of ppar agonism, such...

Stargardt Disease Pathology Stargardt disease is an autosomal recessive disease caused by mutations in the ABCA4 gene. ABCA4 are...

Spinal Muscular Atrophy - Disease Pathology Spinal Muscular Atrophy (SMA) is a genetic condition where the ubiquitously made protein...

Anxiety Disorder Pathology Anxiety is a neuropsychiatry condition, that mainly affects emotion. Neurotransmitters and hormones such as...

Multiple Sclerosis - Disease Pathology Multiple sclerosis also called as T cell mediated autoimmune disease, is a condition where the...

Type II Diabetes - Disease Pathology Type II Diabetes is a condition that arises due to an environment of dysregulated glucose and fat...

Phenylketonuria Disease Pathology Phenylketonuria also called PKU, is a rare inherited disorder which is caused by build up of amino acid...